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Methusalife DNA/RNA Heart Gems: Rejuvenation and Heart Health

    Heart Gems

Research indicates that high Homocysteine levels has been proven to be a major cardiac risk factor; it also advances DNA aging. HeartGems™ contains the amino acid TMG (also called Betaine, naturally derived from beets) that has been found to help support a healthy cardiac nutritional program as well as the natural replication of healthy DNA.


Testimonial: I love the Heart Gems!!! (Thanks to Marisa Morin for recommending them). I'm almost done with my first bottle and my fine motor skills, my stammer, and my brain fog are much improved already.  My mood is also more stable, and my pH has been consistently higher.  Thank you so much for creating and distributing this product.  I want everyone I know and love to take it.  Is there possibly a discount for ordering over a specific amount, so I can get a bottle for everyone, so they can experience the benefits?

Kim G


Testimonial: I took Heartgems between 2007 and 2008, because of a serious recurrence of
heart symptoms, something that has affected me off and on since I was a teenager. The symptoms gradually reduced over a period of about 3 months, till they were altogether gone, and my strength and resilience on every
level had come back up. I would like to take them again now, as I am again having symptoms, but cannot currently afford to do so, unfortunately.
Hopefully that will change eventually.
Annie D 1/27/11


Testimonial: I love the Heart Gems!!! I'm almost done with my first bottle and my fine motor skills, my stammer, and my brain fog are much improved already.  My mood is also more stable, and my pH has been consistently higher.  Thank you so much for creating and distributing this product.  I want everyone I know and love to take it.


We are excited to announce the early results of our major randomized prospective, double blind, placebo controlled, clinical study, the first phase of which focused on the HeartGems formula and its effects on blood chemistry and clinical symptoms.  In the following text are the dramatically positive results and their implications.

The main marker we used for age reversing effects on DNA is called homocysteine.  Recent research indicates the lower the homocysteine, the younger and healthier the condition of DNA.  Homocysteine elevation is also associated with increased cardiovascular risks, with the risk rising exponentially above a level of 6.3, as the following chart indicates:

 Homocysteine Level      <6.3   6.3   10   15   20

Relative Cardiac Risk    <1     1     2    4    9

Thus at a level of 15, the risk of a major cardiac event is 4 times that of the general population.  Also a recent study from Boston University indicates that a level over 14 carries double the risk of Alzheimer’s disease.  Noteworthy is that many labs call a level up to 15 normal, resulting in what is likely widespread under treatment of elevated levels.

In our double blind study 40 subjects above the age of 40 were split randomly into treatment and placebo control groups.  The treatment group took increasing daily amounts of the HEARTGEMS formula equivalent to 6, 12, and 18 capsules for one month each.  The placebo group only received capsules of maltodextrin.

Statistical analysis was done on the results to derive scientific p values.  A p value is the probability that a result will occur by chance alone.  For example, the p value for tossing a tail in a coin flip is .5 or 50%.  Values below .05 or 5% are felt to be statistically significant.  The lower the value, the greater the significance of the results.  A value of .001 is felt to be highly significant, and anything at or below .0001 is very highly significant for the difference between the treatment and control groups.

See Appendix A:  Homocysteine results for the treatment group at baseline, 1, 2, and 3 months are as follows:

                         Baseline            1 month                2 months              3 months

Homocysteine     9.2                         7.1                         6.8                         6.1

P value                                                .00001                   .00001                   .00001

The p values are treatment values compared to baseline, which are all very highly significant.  The entire group, on average reduced to the lowest cardiac risk level.

See Appendix B:  For the placebo control group the values are as follows:

Baseline                1 month                 2 months               3 months

Homocysteine     7.8                         7.3                         7.9                         7.9

P value                                                ns                          ns                          ns

The abbreviation ns means not significant.  There was no significant change in control group levels throughout the course of the study period.

See Appendix C:  Even more dramatic is the reduction in homocysteine for the treatment group subjects that started with high homocysteine levels at or above 10. 

Baseline                1 month                 2 months               3 months

Homocysteine     13.2                       9.3                         8.3                         7.3

P value                                                .009                       .001                       .00001

This drop in homocysteine level is comparable to the chemistry of persons in their 60’s becoming that of persons in their 20’s or 30’s.  As each one-point drop in homocysteine may reduce cardiac risks 10-12%, this suggests an up to 60-70% risk reduction for this group.

Subjects also took intensive symptom surveys that compared them to the general population.  The scores are in percentile rank, the higher the percentile the greater the symptoms.  A person at the 60th percentile has more symptoms of that type than 60% of the population.

See Appendix D:  For the anxiety scale, persons in the treatment group had the following results:

Baseline                1 month                 2 months               3 months

Percentile             56                          40                          27                          24

P value                                                .05                         .0001                                    .0001

This indicates a very highly significant reduction in anxiety scale for the treatment group.  There was no significant reduction in the placebo group.

Further preliminary analysis also suggests significant reductions in somatization or body aches & pains (Appendix E), depression (Appendix F), obsessive compulsive (Appendix G), paranoid (Appendix H), hostility (Appendix I), and global scales (Appendix J)

Appendix E: For Body Aches and Pains

Appendix F:  For Depression

Appendix G: For Obsessive Compulsive

 

Appendix H: For Paroniod

Appendix I: For Hostility

Appendix J: For Global Severity

As the data analysis continues we will strive to share more information as appropriate.

Based on these results, it can be strongly recommended to take 3-6 HEARTGEMS daily for general health and well-being.  Persons with known elevated homocysteine levels may require higher intake amounts for optimum results, best assessed with widely available blood testing.

HEARTGEMS is an activated combination of the most powerful nutrients ever studied for lowering harmful homocysteine in the blood while increasing the production of the highly beneficial SAMe (S-adenosylmethionine).  Homocysteine is highly toxic to blood vessels and its level may be up to 40 times more predictive of the risk of heart disease than the cholesterol level.  44% of U.S. deaths are due to heart disease.  The average homocysteine level in the U.S. population is at an unhealthy 10.  Above the level of 7, every 3-point rise in homocysteine increases heart attack risk by 35%.  Elevated homocysteine levels are also strongly associated with the development of Alzheimer’s disease, strokes, and increased complications in diabetes, lupus, and other chronic diseases.

Homocysteine levels are increased with smoking, alcohol overuse, oral contraceptive use, red meat ingestion, high fat diets, and aging.  One study showed that drinking 4 cups of coffee per day elevates homocysteine levels by 10%.

The action of HEARTGEMS is driven by TMG (trimethylglycine).  See Figure A   TMG provides methyl groups to detoxify homocysteine.  A methyl group consists of a carbon atom attached to three hydrogen atoms.  Methyl groups are widely used in the body for detoxification and DNA repair. Choline also provides methyl groups, but only in the liver and kidneys, and the ingredient inositol may also help to lower homocysteine levels.  Folic acid and vitamins B6 and B12 are key cofactors required for homocysteine detoxification and independently can reduce homocysteine levels.  Zinc is another essential metabolic cofactor for lowering homocysteine that is provided as a highly absorbable and biologically active amino acid chelate.

In almost all cases, adjusting the intake level of this formula to the metabolic situation will be likely to lower homocysteine levels into the lowest risk zone below 7.  Significant homocysteine lowering typically occurs within 1-3 months, which can be validated individually with a homocysteine blood test.  Using this formula, one patient with serious heart disease showed a lowering of homocysteine level from 18 to 4 in only 30 days, equating to an over 90% reduction in cardiac risk and warranting long term life extending use.

In addition to reducing homocysteine levels, the HEARTGEMS formula can also increase the beneficial internal production of methionine, SAMe, DMG (dimethylglycine), glutathione, and melatonin.   For example, ingestion of the HEARTGEMS formula at higher levels may increase SAMe by 400%.  Some of the more significant reported benefits of these internal HEARTGEMS byproducts are summarized in the following table:

Methyl Group Donation (TMG, SAMe, and Choline)

  • Methyl groups break down harmful chemicals.
  • Required for growth of new cells.
  • Prevents DNA mutations and strand breaks.
  • Protects against alcohol induced liver injury.
  • May slow and even reverse aging

SAMe (S-adenosylmethionine)

  • Increases serotonin levels and can be a potent mood elevator.
  • Helps repair and preserve joint function.
  • Potent relief of joint pain.
  • Cell membrane stabilizer.
  • Intimately involved in DNA protection and repair.
  • Enhances ATP, the fundamental cellular energy molecule.
  • Well being promoter.
  • Repairs liver injury.
  • Protects the heart.
  • Builds myelin sheaths around nerves.
  • Maintains and repairs brain cells.

Melatonin

  • Promotes rejuvenative sleep.
  • Immune enhancer.

Glutathione

  • One of the most powerful antioxidants ever studied.
  • Anti-aging actions.

DMG (Dimethylglycine)

  • Increases physical energy.
  • Enhances athletic performance.

Folic Acid

  • Decreases incidence of birth defects.

Lipotropic or Fat-directed Factors (Methionine, Choline, and Inositol)

  • Improves fluidity of cell membranes (required for cell regeneration).
  • Supports production and repair of myelin sheaths of nerves.
  • Detoxifies heavy metals and environmental toxins.
  • Reduces toxic effects of cigarette smoke and smog.
  • Protects against injury from ionizing radiation.
  • May enhance learning and memory.
  • Improves metabolism of fat and cholesterol.

The HEARTGEMS components are activated with a patented laser technology designed to energize the methyl groups of trimethylglycine and promote their transfer. 

A 1998 article in Medical Hypothesis presents evidence that aging may be almost entirely due to a loss of methyl groups within the cells, with elevated homocysteine a marker for impaired methyl group transfers throughout the body.  This study concludes that aging may be reversible if aged cells could be stimulated to restore methyl group transfer functions rather than losing them.  HEARTGEMS provides all the essential factors required for methyl group transfers.

The recommended use of HEARTGEMS is one capsule three times daily with meals.  For many persons, this level of intake will reduce homocysteine levels to the lowest risk range.  Some persons may require 3-6 times this basic amount for optimum results.  This is especially true for persons with marked elevations of homocysteine, or for persons with severe liver disease or genetic enzyme abnormalities. Enhanced mood and increased physical energy are markers that suggest adequate intake.  Blood testing for homocysteine levels is the most certain way to be sure the desired results have been achieved. 

Homocysteine Level Cardiac Risk Level
< 6.3 <1x greater risk
6.3 1x greater risk
10 2x greater risk
15 4x greater risk
20 9x greater risk

It is suggested that one capsule three times per day be taken for the first month.  After that, the use can be increased to strive for desired levels of energy and mood enhancement, relief of joint symptoms, or support of liver or brain nutrition.  This formula is a long-term rebuilder, restorer, and preventative, and usually requires several weeks of use before the effects are perceived.

The components of the formula are very safe.  TMG has no side effects except for brief tension headaches if large quantities are taken on an empty stomach.  Choline may occasionally deepen the depressive phase of manic-depressive illness.  Chronic intake of large amounts of vitamin B6, over 300-500mg per day, may rarely cause nerve inflammation.  Even at the highest suggested intake of HEARTGEMS, this threshold for B6 would not be exceeded.  Although up to nine capsules three times per day may be safely taken, clinical studies have not shown further benefit beyond the levels of 6 capsules three times per day.

Persons who have taken this homocysteine lowering combination of nutrients for 10 or more years report a marked reduction in colds, increased energy and endurance, and reduced blood sugar levels.  Fat may melt off the body with ease with a return to more youthful body proportions.  Some people describe that this nutrient blend makes them feel like young adults or even teenagers again.

Extended use of this formula is therefore recommended to get the greatest possible individual benefits.  Based on cardiac risk factor reduction considerations alone, it is estimated that with long term use each serving of HEARTGEMS may extend life 15 minutes or more.  HEARTGEMS may be the most powerful life extending and enhancing formula ever offered. 

A Word on Heavy Metal Toxicities

We have some new, exciting news regarding our HeartGems product.   The product was being tested by a holistic dentist in Canada who, for the past 4 years, has been seeking a product that can help his patients with heavy metal toxicities.  He does fecal elements tests to determine the amount of toxins that are being excreted.  He decided to test the product on himself because he has no heavy metal toxicity (no more than any of us do!) He likes to see what results he would get personally before testing it on his patients.  He went on the product for 6 days taking 6 caps/day.  He says it typically takes only 6 days if you are going to see any difference at all. He was astounded with the results, which were fantastic!  The excretion of Mercury, Lead, Arsenic, Nickel, & Tungsten were dramatically increased.  Anywhere from 3 to 40 times as much as before taking the HeartGems!!  Very encouraging.  He says that in his past 4 years of searching he has never seen a product work so well.  He mentioned that many times other products he used would dramatically increase the excretion of 1 metal but for reasons unknown would actually DECREASE the excretion of others!  HeartGems had increases across the board with the exception of copper, which was the only metal tested, that remained the same.

 

Doctor’s Data Lab Test Evaluation:

      PRE   mg/kg             METALS                                            POST  mg/kg

      0.024                      <.05 w/o amalgams Mercury                   0.083

      0.024                      <.05 with amalgams Mercury             0.083

      0.036                                     Antimony                                               0.093

      0.15                          Arsenic                                                  0.20

      < dl                           Beryllium                                                0.004

      0.025                        Bismuth                                                 0.070

      0.68                          Cadmium                                               0.73

      50                             Cooper                                                    49

      0.37                           Lead                                                      0.53

      5.3                            Nickel                                                     6.1

      < dl                           Platinum                                                 <dl

      0.019                        Thallium                                                 0.025

      0.020                        Tungsten                                                0.758

      0.137                        Uranium                                                 0.149

 

Suggested Usage:  Take 1 capsule with each meal or as directed.

Precautions:  Advised against in persons with manic depressive illness or those taking anti-depressants such as SSRIs, Tricyclics, or MAO inhibitors because of the use of the ingredient Choline. 

Ingredients: Trimethylglycine, Choline Bitartrate, Inositol-proprietary blend of 1.62 g, Vitamin B3 (as insotal hexanicotinate) – 150mg, Vitamin B6 (as pyridoxine hydrochloride-25mg and as pyridoxal-5-phosphate-5mg), Vitamin B12 (as cyanocobalamin with dibasic calcium phosphate)-500mcg, Folate (as folic acid)-800mcg Magnesium (from magnesium chelate)-15mg, and Zinc (from Zinc chelate)-2.5mg. Also contains  calcium chloride and may contain silicon dioxide.

HeartGems 90 Capsules $36.77

Quantity:
 

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These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. If under medical care, or if pregnant or nursing, please consult a health professional.